Vol. 4 No. 2 (2024): Hong Kong Journal of AI and Medicine
Articles

Machine Learning Models for Predicting Drug Efficacy and Side Effects: Developing machine learning models to predict drug efficacy and potential side effects based on patient characteristics and pharmacogenomic data, aiding in treatment selection and pers

Dr. Sarah Miller
Professor of Health Informatics, University of Technology Sydney, Australia

Published 21-09-2024

Keywords

  • Machine learning

How to Cite

[1]
Dr. Sarah Miller, “Machine Learning Models for Predicting Drug Efficacy and Side Effects: Developing machine learning models to predict drug efficacy and potential side effects based on patient characteristics and pharmacogenomic data, aiding in treatment selection and pers”, Hong Kong J. of AI and Med., vol. 4, no. 2, pp. 25–32, Sep. 2024, Accessed: Nov. 27, 2024. [Online]. Available: https://hongkongscipub.com/index.php/hkjaim/article/view/29

Abstract

This paper presents a comprehensive review and analysis of machine learning (ML) models for predicting drug efficacy and side effects. The rapid advancement of ML techniques, coupled with the availability of large-scale pharmacogenomic and patient data, has enabled the development of predictive models that can assist in treatment selection and personalized medicine. We discuss various ML algorithms, data sources, and feature selection techniques used in this domain. Additionally, we highlight challenges, such as data heterogeneity and model interpretability, and propose future research directions to enhance the accuracy and usability of these models.

Downloads

Download data is not yet available.

References

  1. Saeed, A., Zahoor, A., Husnain, A., & Gondal, R. M. (2024). Enhancing E-commerce furniture shopping with AR and AI-driven 3D modeling. International Journal of Science and Research Archive, 12(2), 040-046.
  2. Biswas, Anjanava, and Wrick Talukdar. "Guardrails for trust, safety, and ethical development and deployment of Large Language Models (LLM)." Journal of Science & Technology 4.6 (2023): 55-82.
  3. N. Pushadapu, “Artificial Intelligence for Standardized Data Flow in Healthcare: Techniques, Protocols, and Real-World Case Studies”, Journal of AI-Assisted Scientific Discovery, vol. 3, no. 1, pp. 435–474, Jun. 2023
  4. Chen, Jan-Jo, Ali Husnain, and Wei-Wei Cheng. "Exploring the Trade-Off Between Performance and Cost in Facial Recognition: Deep Learning Versus Traditional Computer Vision." Proceedings of SAI Intelligent Systems Conference. Cham: Springer Nature Switzerland, 2023.
  5. Alomari, Ghaith, et al. “AI-Driven Integrated Hardware and Software Solution for EEG-Based Detection of Depression and Anxiety.” International Journal for Multidisciplinary Research, vol. 6, no. 3, May 2024, pp. 1–24.
  6. Choi, J. E., Qiao, Y., Kryczek, I., Yu, J., Gurkan, J., Bao, Y., ... & Chinnaiyan, A. M. (2024). PIKfyve, expressed by CD11c-positive cells, controls tumor immunity. Nature Communications, 15(1), 5487.
  7. Borker, P., Bao, Y., Qiao, Y., Chinnaiyan, A., Choi, J. E., Zhang, Y., ... & Zou, W. (2024). Targeting the lipid kinase PIKfyve upregulates surface expression of MHC class I to augment cancer immunotherapy. Cancer Research, 84(6_Supplement), 7479-7479.
  8. Gondal, Mahnoor Naseer, and Safee Ullah Chaudhary. "Navigating multi-scale cancer systems biology towards model-driven clinical oncology and its applications in personalized therapeutics." Frontiers in Oncology 11 (2021): 712505.
  9. Saeed, Ayesha, et al. "A Comparative Study of Cat Swarm Algorithm for Graph Coloring Problem: Convergence Analysis and Performance Evaluation." International Journal of Innovative Research in Computer Science & Technology 12.4 (2024): 1-9.
  10. Pelluru, Karthik. "Cryptographic Assurance: Utilizing Blockchain for Secure Data Storage and Transactions." Journal of Innovative Technologies 4.1 (2021).